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*******************<br/><b>Commercial Name:</b> Topamax <br/><br/><b>Active Ingredient:</b> Topiramate<br/><br/><b>Utilization:</b> Used to treat convulsions, epilepsy in children and adults, and also to prevent migraines and certain psychiatric conditions<br/>Available Dosages: 25mg, 50mg, 100mg and 200mg
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Drug-drug interaction studies conducted under single dose conditions in healthy volunteers and multiple dose topamax conditions in patients with bipolar disorder, yielded similar results .
When administered concomitantly with topiramate at escalating doses of 100, 250 and 400 mg/day there was a reduction in risperidone (administered at doses ranging from 1 to 6 mg/day) systemic exposure (16% and 33% for steady-state AUC at the 250 topamax and vision topamax and dry mouth is topamax the same as topiramate topamax adverse effects and 400 mg/day doses, respectively) .
However, differences in AUC for the total active moiety between treatment with risperidone alone and combination treatment with topiramate topamax were not statistically significant .
Minimal alterations in the pharmacokinetics of the total active moiety (risperidone plus 9hydroxyrisperidone) and no alterations topamax permanent side effects topamax dry eyes can you drink alcohol while taking topamax topamax for 9-hydroxyrisperidone were observed .
There were no significant changes in the systemic exposure of the risperidone total topamax active moiety or of topiramate .
topamax for migraines side effects topamax mental health topamax 150 mg topamax side effects reviews When topiramate was added to existing risperidone (1-6 mg/day) treatment, adverse events were reported more frequently than prior to topiramate (250-400 mg/day) introduction (90% and 54 % respectively) .
The most frequently reported AE’s when topiramate was added to risperidone treatment were: somnolence (27% and 12%), paraesthesia (22% and 0%) topamax half life what is topamax 25mg used for how to come off topamax headache medicine topamax and nausea (18% and 9% respectively) .topamax side effects weight gain |
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