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15 décembre 2020 à 5 h 11 min #37128clarisnelsonParticipant
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8 USE IN Sometimes, dextroamphetamine and amphetamine may harm the human body. These are, in turn, termed to SPECIFIC POPULATIONS Teratogenic Effects Pregnancy Category C .
Amphetamine, in the enantiomer ratio present in ADDERALL XR (d- to l- ratio of 3:1), had no apparent effects on embryofetal morphological development or survival when orally administered to pregnant adderall dosage experience adderall 20 mg adderall bid dosing adderall xr 5mg adderall on empty rats and rabbits throughout the period of organogenesis at doses of up to 6 and 16 mg/kg/day, respectively .
These doses are approximately 2 and 12 times, respectively, the maximum recommended human dose (MRHD) for adolescents of 20 mg/day, on adderall xr weight adderall gas bloating adderall xr xanax adderall xr vs ritalin adderall yellow a mg/m2 body surface area basis .
Fetal malformations and death have been reported in mice following parenteral administration of d-amphetamine doses of 50 mg/kg/day (approximately 10 times the MRHD for adolescents on a mg/m2 basis) or amphetamine greater to pregnant animals .
Administration of these amphetamine doses was also associated with severe maternal toxicity .
A study was conducted in which pregnant rats received daily oral doses of amphetamine (d- to l- enantiomer ratio of 3:1, the same as in ADDERALL XR) of 2, amphetamine 6, and 10 mg/kg from gestation day 6 to lactation day 20 .
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